Welcome to smProdrugs

smProdrugs, a database of small molecule prodrugs, is a consolidated data source of the small molecule prodrugs and information on their structure, experimental and predicted ADMET properties, physicochemical properties etc., which will be useful for researchers who attempt to rationally design a prodrug. Following are few salient features of the database.

Highlights

More than 625 small molecule prodrug entries including approved drugs and those in clinical trials, experimental stage

Structural comparison of Prodrugs and their active drugs and structures downloadable in .smi, .mol and .sdf formats

Comparative ADMET properties of prodrugs and active drugs

Pharmacological targets, indications and activating enzymes

Information retrival from smProdrugs

Search Facilities: The users can search smProdrugs to retrieve information on Prodrugs, ADMET and other properties, Targets and Prodrug Activating enzymes. Information on prodrugs can be obtained through (i) Prodrug name, (ii) Target, (iii) PubChemID and (iv) Disease.

Advanced structure Search: Web based tools integrated in smProdrugs allows users to draw the query structure, paste/upload the query structure in .sdf, .mol and .smi formats. Options to perform exact structure search as well as substructure or superstructure search are also available.

Browsing: This section enables the users to catagorically fetch the data based on Prodrug and active drug names (alphabetically), Targets, Disease and improvement in properties by the prodrug aproach

Mobile Compatible Website: smProdrugs is compatible for desktop, tablet and smart phone.