Showing results for 'A'
Total number of hits: 67
Click on results for more details:
PDIDA001
Abiraterone acetate
Active compound: Abiraterone
Indications: Prostate cancer
Target: 17 α-hydroxylase/C17,20-lyase (CYP17)
PDIDA002
AC1L9V0Z
Active compound: Echinocandin B
Indications: Pneumocystis carinii pneumonia
Target: na
PDIDA003
AC1L9V12
Active compound: Echinocandin B
Indications: Pneumocystis carinii pneumonia
Target: na
PDIDA004
AC1L9V15
Active compound: Echinocandin B
Indications: Pneumocystis carinii pneumonia
Target: na
PDIDA005
AC1L9WBZ
Active compound: Lamivudine
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA006
AC1L9WC2
Active compound: Lamivudine
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA007
AC1L9WC5
Active compound: Lamivudine
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA008
AC1L9WC8
Active compound: Lamivudine
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA009
AC1L9WCB
Active compound: FTC
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA010
AC1L9WCE
Active compound: FTC
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA011
AC1LA7FB
Active compound: KNI-279
Indications: HIV infection
Target: HIV Protease
PDIDA012
AC1LAEL0
Active compound: KNI-225
Indications: HIV infection
Target: HIV Protease
PDIDA013
AC1LAHXM
Active compound: 3'-Fluoro-3'-deoxythymidine
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA014
AC1LAHXP
Active compound: 3'-Fluoro-3'-deoxythymidine
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA015
AC1LAHXS
Active compound: 3'-Fluoro-3'-deoxythymidine
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA016
AC1LAHZV
Active compound: 3'-Fluoro-3'-deoxythymidine
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA017
AC1LANX6
Active compound: KNI-227
Indications: HIV infection
Target: HIV Protease
PDIDA018
AC1MHEO9
Active compound: 2-Amino-6-methoxypurine analogue
Indications: Cytomegalo Virus Infection
Target: DNA
PDIDA019
AC1NUIF5
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA020
AC1NUIZT
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDA021
Aceburic acid
Active compound: Gamma-hydroxybutyrate
Indications: Anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance.
Target: Cell specific
PDIDA022
Acediasulfone
Active compound: Dapsone
Indications: Ear infection; Leprosy
Target: Dihydropteroate synthetase
PDIDA023
Aceglutamide
Active compound: L-glutamine
Indications: Sickle cell disease
Target: Cell specific
PDIDA024
Acemetacin
Active compound: Indometacin
Indications: Osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain
Target: Cyclooxygenase (COX)
PDIDA025
Acetadote
Active compound: L-cysteine
Indications: HIV infection
Target: Glutathione synthetase; Cystine/glutamate transporter
PDIDA026
Acetyl sulfisoxazole
Active compound: Sulfisoxazole
Indications: Urinary tract infections
Target: Dihydropteroate synthase
PDIDA027
Aciclovir
Active compound: Aciclovir triphosphate
Indications: HSV viral infection
Target: DNA polymerase
PDIDA028
Aconiazide
Active compound: Isoniazide
Indications: Tuberculosis
Target: Cell specific
PDIDA029
Adefovir Dipivoxil
Active compound: Adefovir
Indications: Hepatitis b virus
Target: Reverse transcriptase
PDIDA030
Adenosine
Active compound: Adenosine Monophosphate
Indications: Paroxysmal supraventricular tachycardia (PVST); Narrow-complex supraventricular tachycardias (SVT)
Target: Adenosine receptor
PDIDA031
Adrafinil
Active compound: Modafinil
Indications: Wakefulness for excessive daytime sleepiness (EDS)
Target: α1-adrenergic receptor
PDIDA032
AKOS024372695
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDA033
Alacepril
Active compound: Captopril
Indications: Hypertension and congestive heart failure
Target: Angiotensin-converting-enzyme inhibitor
PDIDA034
Alalevonadifloxacin
Active compound: Levonadifloxacin
Indications: Acute bacterial skin and skin structure infections (ABSSSI)
Target: DNA gyrase
PDIDA035
Alamifovir
Active compound: SCHEMBL6664903
Indications: Hepatitis B virus
Target: Inhibiting viral DNA priming and viral DNA packaging
PDIDA036
Alatrofloxacin
Active compound: Trovafloxacin
Indications: Broad spectrum antibiotic
Target: DNA gyrase and DNA topoisomerase IV activities
PDIDA037
Aldoxorubicin
Active compound: Doxorubicin
Indications: Solid tumors
Target: DNA topoisomerase 2-alpha
PDIDA038
Alestramustine
Active compound: Estramustine
Indications: Metastatic and/or progressive carcinoma of the prostate
Target: Microtubule-associated proteins and β-tubulin
PDIDA039
Alfacalcidol
Active compound: Vitamin D3
Indications: Regulation of the calcium balance and the bone metabolism
Target: Vitamin D3 receptor
PDIDA040
Allopurinol
Active compound: Oxypurinol
Indications: Chronic gout
Target: Xanthine oxidase
PDIDA041
Allylestrenol
Active compound: 17α-allyl-19-nortestosterone
Indications: Treat recurrent and threatened miscarriage and to prevent premature labor in pregnant women
Target: Progesterone, androgen and glucocorticoid receptors
PDIDA042
ALS-8176
Active compound: ALS-8112
Indications: RSV infection
Target: RSV polymerase
PDIDA043
Amelubant
Active compound: BIIL-315 (Metabolite 2)
Indications: Asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and rheumatoid arthritis
Target: Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2
PDIDA043
Amelubant
Active compound: BIIL-260 (Metabolite 1)
Indications: Asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and rheumatoid arthritis
Target: Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2
PDIDA062
Astarabine
Active compound: Ara-CTP
Indications: Acute myeloid leukemia (AML)
Target: DNA, DNA Polymerase
PDIDA044
Amfecloral
Active compound: Phenethylamine
Indications: Scizophrenia
Target: Cell system
PDIDA045
Amfetaminil
Active compound: Amphetamine
Indications: Fatigue, Depression, potency disorders, Narcolepsy, childhood hyperkinesis
Target: Synaptic vesicular amine transporter; Sodium-dependent dopamine transporter
PDIDA046
Amifostine
Active compound: WR-1065
Indications: Cytoprotective adjuvant used in cancer
Target: na
PDIDA047
Ampiroxicam
Active compound: Piroxicam
Indications: Rheumatoid arthritis and osteoarthritis
Target: Cyclooxygenase (COX)
PDIDA048
AN-9
Active compound: Butyric acid
Indications: Liver cancer, lung cancer, melanoma, and leukemia
Target: Histone deacetylase
PDIDA049
ANA971
Active compound: Isatoribine
Indications: Hepatitis C virus
Target: Toll-like receptor 7
PDIDA050
Androstanolone benzoate
Active compound: Dihydrotestosterone
Indications: Na
Target: Androgen receptor
PDIDA051
Androstanolone enanthate
Active compound: Dihydrotestosterone
Indications: Na
Target: Androgen receptor
PDIDA052
Androstanolone propionate
Active compound: Dihydrotestosterone
Indications: Na
Target: Androgen receptor
PDIDA053
Androstanolone valerate
Active compound: Dihydrotestosterone
Indications: Na
Target: Androgen receptor
PDIDA054
Aniline mustard glucuronide
Active compound: Aniline mustard
Indications: Colon cancer
Target: Beta-glucuronidase-positive cells
PDIDA055
Apaziquone
Active compound: Semi-quinone radical form of EO9
Indications: Breast and lung cancer
Target: DNA minor grove
PDIDA056
Arbaclofen placarbil
Active compound: R-baclofen
Indications: Treatment for patients with GERD and spasticity due to multiple sclerosis
Target: Gamma-aminobutyric acid type B receptor subunit 1; Gamma-aminobutyric acid type B receptor subunit 2
PDIDA057
Aripiprazole cavoxil
Active compound: Aripiprazole
Indications: bipolar disorder
Target: Dopamine receptor
PDIDA058
Aripiprazole lauroxil
Active compound: Aripiprazole
Indications: Schizophrenia; senile dementia; transient psychosis following surgery; or Myocardial infaraction
Target: Dopamine D2 receptor; 5-hydroxytryptamine receptor 1A; 5-hydroxytryptamine receptor 2A
PDIDA059
Artemisinin
Active compound: Dihydroartemisinin
Indications: Malaria
Target: Heme present in the hemozoin and hemoglobin; histidine-rich protein II (PfHRP II)
PDIDA060
Artesunate
Active compound: Dihydroartemisinin
Indications: Malaria
Target: Malaria proteins EXP1
PDIDA061
Ascorbate
Active compound: Hydrogen peroxide
Indications: Tuberculosis
Target: DNA
PDIDA063
Atovaquone prodrug
Active compound: Atovaquone
Indications: Pneumocystis carinii infection
Target: Cytochrome bc1 complex (Complex III)
PDIDA064
Avizafone
Active compound: Diazepam
Indications: Anxiolytic agent and muscle relaxant,premediation for anesthesia, a sedative for minor surgery or invasive procedures, and for treatment of status epileptus or severe recurrent seizures
Target: Acetylcholinesterase
PDIDA065
Azathioprine
Active compound: 6-Mercaptopurine
Indications: Cancer, autoimmune disorders and in organ transplant
Target: Hypoxanthine-guanine phosphoribosyltransferase
PDIDA066
Azilsartan Medoxomil
Active compound: Azilsartan
Indications: Essential hypertension
Target: Type-1 angiotensin II receptor