Showing results for 'S'
Total number of hits: 36
Click on results for more details:
PDIDC064
CID 132564392
Active compound: SN-38
Indications: Cancer
Target: DNA topoisomerase I inhibitor
PDIDC065
CID 132564393
Active compound: SN-38
Indications: Cancer
Target: DNA topoisomerase I inhibitor
PDIDC072
CID 71763696
Active compound: SCHEMBL5341592
Indications: P. aeruginosa
Target: na
PDIDC073
CID 72191181
Active compound: SCHEMBL14517194
Indications: P. aeruginosa
Target: na
PDIDC092
Ciprofloxacin prodrug of stavudine
Active compound: Stavudine
Indications: Tuberculosis
Target: Reverse transcriptase/RnaseH
PDIDD022
Dimethylamine prodrug of stavudine
Active compound: Stavudine
Indications: Tuberculosis
Target: Reverse transcriptase/RnaseH
PDIDI010
Isoniazide prodrug of stavudine
Active compound: Stavudine
Indications: Tuberculosis
Target: Reverse transcriptase/RnaseH
PDIDL004
Lansoprazole
Active compound: Sulfenamide form of Lansoprazole
Indications: Erosive reflux oesophagitis, active gastric ulcer, active duodenal ulcer, tuberculosis
Target: (H+,K+)-ATPase
PDIDM005
Menadione
Active compound: Semiquinone radical
Indications: iver, colon, lung, stomach, and prostateand leukemia
Target: DNA
PDIDN011
Norfloxacin prodrug of stavudine
Active compound: Stavudine
Indications: Tuberculosis
Target: Reverse transcriptase/RnaseH
PDIDN017
NSC-731657
Active compound: STAVUDINE
Indications: HIV infection
Target: Reverse Transcriptase
PDIDN018
NSC-731658
Active compound: STAVUDINE
Indications: HIV infection
Target: Reverse Transcriptase
PDIDO005
Omeprazole
Active compound: Sulfenamide form of Omeprazole
Indications: Peptic ulcers, zollinger–ellison syndrome, erosive reflux oesophagitis; gastric ulcers
Target: (H+,K+)-ATPase
PDIDP005
Pantoprazole
Active compound: Sulfenamide form of Pantoprazole
Indications: Erosive esophagitis associated with gastroesophageal reflux disease (gerd)
Target: (H+,K+)-ATPase
PDIDA026
Acetyl sulfisoxazole
Active compound: Sulfisoxazole
Indications: Urinary tract infections
Target: Dihydropteroate synthase
PDIDP015
Phthalylsulfathiazole
Active compound: Sulfathiazole
Indications: Na
Target: Dihydropteroate synthase
PDIDP017
Piperazine prodrug of Stavudine
Active compound: Stavudine
Indications: HIV/AIDS
Target: Reverse transcriptase/RnaseH
PDIDP038
Progabide
Active compound: SL-75102
Indications: Epilepsy
Target: GABAA, GABAB, and GABAA-ρ receptors
PDIDP042
Prontosil
Active compound: Sulfanilamide
Indications: Erysipelas (R1)
Target: Dihydropteroate synthase
PDIDP047
pyrazinamide prodrug of stavudine
Active compound: Stavudine
Indications: Tuberculosis
Target: Reverse transcriptase/RnaseH
PDIDR004
Rabeprazole
Active compound: Sulfenamide form of Rabeprazole
Indications: Erosive esophagitis associated with gastroesophageal reflux disease (gerd)
Target: na
PDIDS001
Sacubitril
Active compound: Sacubitrilat
Indications: Reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction
Target: Neprilysin (WL1)
PDIDS003
SB 204990
Active compound: SB 201076
Indications: Hypolipidaemia
Target: ATP citrate (pro-S)-lyase
PDIDS004
SCHEMBL10193041
Active compound: SN-38
Indications: Cancer
Target: DNA topoisomerase I inhibitor
PDIDA035
Alamifovir
Active compound: SCHEMBL6664903
Indications: Hepatitis B virus
Target: Inhibiting viral DNA priming and viral DNA packaging
PDIDS031
Secnidazole
Active compound: Secnidazole active nitro radical
Indications: Bacterial vaginosis in adult women
Target: Bacterial DNA synthesis
PDIDS033
Sergliflozin etabonate
Active compound: Sergliflozin
Indications: Type 2 diabetes mellitus (R1)
Target: Sodium-dependent glucose cotransporter 2 (sglt2) (r1)
PDIDS038
Simvastatin
Active compound: Simvastatin acid
Indications: Dyslipidemia, elevated lipid levels
Target: 3-hydroxy-3-methylglutaryl (HMG) coenzyme reductase
PDIDS040
SNX-5422
Active compound: SNX-2112
Indications: Breast, lung, and ovarian cancer
Target: Heat shock protein HSP 90
PDIDS042
Spirapril
Active compound: Spiraprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDS043
Spiruchostatin (A)
Active compound: Spiruchostatin A (reduced)
Indications: Breast cancer
Target: Histone deacetylase (HDAC) (R1, R2)
PDIDS044
Stampidine
Active compound: Stavudine
Indications: HIV
Target: Non-nucleoside reverse transcriptase
PDIDS046
Succinylsulfathiazole
Active compound: Sulfathiazole
Indications: Na
Target: Dihydropteroate synthase
PDIDS047
Sulfasalazine
Active compound: Sulfapyridine
Indications: Rheumatoid arthritis
Target: Prostaglandin G/H synthase
PDIDS048
Sulindac
Active compound: Sulindac Sulfide
Indications: Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute painful shoulder and acute gouty arthritis
Target: Prostaglandin G/H synthase 2
PDIDA055
Apaziquone
Active compound: Semi-quinone radical form of EO9
Indications: Breast and lung cancer
Target: DNA minor grove