Showing results for 'C'
Total number of hits: 114
Click on results for more details:
PDIDC001
Candesartan Cilexetil
Active compound: Candesartan
Indications: Hypertension
Target: Angiotensin ii receptor
PDIDC002
Candoxatril
Active compound: Candoxatrilat
Indications: heart failure
Target: Neutral endopeptidase and ACE
PDIDC003
Canfosfamide
Active compound: Bis[bis(2-chloroethyl)amino]phosphinate
Indications: Colon and breast carcinoma
Target: DNA
PDIDC004
Canrenoate
Active compound: Canrenone
Indications: Hypertension (R1)
Target: Mineralocorticoid receptor
PDIDC005
Capecitabine
Active compound: Fluorouracil
Indications: Candida or Cryptococcus neoformans fungal infections
Target: Thymidylate synthase (TS); DNA; RNA
PDIDC006
Carfecillin
Active compound: Carbenicillin
Indications: Chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria.
Target: Penicillin binding protein
PDIDC007
Carindacillin
Active compound: Carbenicillin
Indications: Gram-negative bacterial infection
Target: Penicillin-sensitive transpeptidase c-terminal domain
PDIDC008
Carisoprodol
Active compound: Meprobamate
Indications: Painful muscle spasms
Target: GABAA receptors
PDIDC009
Carmofur
Active compound: Fluorouracil
Indications: Breast and GI cancer
Target: Thymidylate synthase
PDIDC010
Cbz–Ser–Ser–Phe–Tyr linked prodrug of 4-aminocylophosphamide
Active compound: Phosphoramide mustard
Indications: Prostate cancer
Target: na
PDIDC011
CDB-4754
Active compound: 11β-MNT
Indications: Na
Target: na
PDIDC012
CDP323
Active compound: Zaurategrast
Indications: Multiple sclerosis (MS)
Target: Integrin alpha-4
PDIDC013
Cefamandole nafate
Active compound: Cefamandole
Indications: Bacterial Infections
Target: Penicillin-binding protein 2
PDIDC014
Cefcapene pivoxil
Active compound: Cefcapene
Indications: Palmoplantar pustulosis (PPP), Bacterial Infections
Target: Penicillin binding protein
PDIDC015
Cefditoren pivoxil
Active compound: Cefditoren
Indications: Throat and lung infections, including bronchitis and tonsillitis
Target: Penicillin binding protein
PDIDC016
Cefotiam hexetil
Active compound: Cefotiam
Indications: Surgical infection, postoperative infections, bacterial septicaemia, bone and joint infections, cholangitis, cholecystitis, peritonitis, prostatitis, pyelonephritis, respiratory tract infections, skin and soft tissue infections, cystitis, urethritis, and infections caused by susceptible organisms
Target: Penicillin binding protein 1A. 1B and 3 of E. Coli
PDIDC017
Cefpodoxime Proxetil
Active compound: Cefpodoxim
Indications: Gram-positive and Gram-negative bacterial infection
Target: Penicillinases and cephalosporinases
PDIDC018
Ceftaroline Fosamil
Active compound: Ceftaroline
Indications: Acute bacterial skin infections; Community-acquired bacterial pneumonia
Target: Bacterial penicillin-binding protein (ChEMBL)
PDIDC019
Cefteram pivoxil
Active compound: Cefteram
Indications: Laryngopharyngitis,tonsillitis, acute bronchitis, pneumonia, chronic bron-chitis, diffuse panbronchiolitis, infected bronchiec-tasis and other infective chronic respiratory diseases
Target: Penicillin binding protein
PDIDC020
Ceftizoxime alapivoxil
Active compound: Ceftizoxime
Indications: Bacterial Infections
Target: Penicillin binding protein
PDIDC021
Ceftobiprole medocaril
Active compound: Ceftobiprole
Indications: Hospital-acquired pneumonia (HAP) and community-acquired pneumonia (CAP)
Target: Penicillin-binding proteins (PBPs)
PDIDC022
Cefuroxime axetil
Active compound: Cefuroxime
Indications: Bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Target: Penicillin-binding protein 1A
PDIDC023
Cefuroxime pivoxetil
Active compound: Cefuroxime
Indications: Na
Target: Penicillin binding protein
PDIDC024
CEP-7055
Active compound: CEP-5214
Indications: Brain tumors and colon carcinoma
Target: Pan vascular endothelial growthfactors (VEGF) kinase
PDIDC025
CHEMBL1205526
Active compound: Triapine
Indications: Lung carcinoma
Target: Ribonucleotide reductase
PDIDC026
CHEMBL1615593
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC027
CHEMBL1802093
Active compound: DOPAC
Indications: Lung, ovary and breast cancer
Target: Tyrosine kinases
PDIDC028
CHEMBL2063119
Active compound: Afimoxifene
Indications: Breast cancer
Target: Estrogen receptor
PDIDC029
CHEMBL2079244
Active compound: Afimoxifene
Indications: Breast cancer
Target: Estrogen receptor
PDIDC030
CHEMBL32085
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC031
CHEMBL497111
Active compound: Adamantamine
Indications: Parkinson’s disease (PD)
Target: Glutamate receptor ionotropic, NMDA
PDIDC032
CHEMBL497112
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC033
CHEMBL590229
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC034
CHEMBL598828
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC035
CHEMBL598829
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC036
CHEMBL62755
Active compound: Phenylmethaneselenol
Indications: Kidney cancer
Target: na
PDIDC037
Chloral hydrate
Active compound: Trichloroethanol
Indications: Sedative-hypnoticdrug
Target: Barbiturate recognition site on GABA-A receptors
PDIDC038
Chloramphenicol palmitate
Active compound: Chloramphenicol
Indications: Bacterial infection
Target: 50S ribosomal subunit
PDIDC039
Chloramphenicol stearate
Active compound: Chloramphenicol
Indications: Bacterial infection
Target: 50S ribosomal subunit
PDIDC040
Chloramphenicol succinate
Active compound: Chloramphenicol
Indications: Typhoid fever, salmonella septicaemia
Target: 50S ribosomal subunit
PDIDC041
Chlorotrianisene
Active compound: Triphenylethylene
Indications: Hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias
Target: Estrogen receptor
PDIDC042
Ciclesonide
Active compound: Desisobutyrylciclesonide
Indications: Asthma and allergic rhinitis
Target: Glucocorticoid receptor
PDIDC043
CID 10009229
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC044
CID 10089832
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC045
CID 101239087
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC046
CID 101239088
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC047
CID 101239089
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC048
CID 101239091
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC049
CID 101239092
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC050
CID 101458753
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC051
CID 101681216
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC052
CID 101681217
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC053
CID 101681218
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC054
CID 102239065
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC055
CID 10439599
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC056
CID 10621768
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC057
CID 10937253
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC058
CID 11796118
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC059
CID 12004257
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC060
CID 129866160
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDC061
CID 129866166
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDC062
CID 129866179
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDC063
CID 129866181
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDC064
CID 132564392
Active compound: SN-38
Indications: Cancer
Target: DNA topoisomerase I inhibitor
PDIDC065
CID 132564393
Active compound: SN-38
Indications: Cancer
Target: DNA topoisomerase I inhibitor
PDIDC066
Cid 14756455
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC067
CID 20301216
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC068
CID 21390763
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC069
CID 21426279
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC070
CID 44267476
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC071
CID 44267505
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC072
CID 71763696
Active compound: SCHEMBL5341592
Indications: P. aeruginosa
Target: na
PDIDC073
CID 72191181
Active compound: SCHEMBL14517194
Indications: P. aeruginosa
Target: na
PDIDC074
CID 73317165
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC075
CID 74983874
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC076
CID 74983875
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC077
CID 75242292
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC078
CID 75242294
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC079
CID 75243316
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC080
CID 75243318
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC081
CID 75243320
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC082
CID 75243324
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC083
CID 75243326
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC084
CID 76723249
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC085
CID 76723253
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC086
CID 76723259
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC087
CID 85143503
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC088
CID 86157027
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDC089
Cidofovir
Active compound: Cidofovir diphosphate
Indications: Cytomegalovirus (CMV)
Target: Viral DNA
PDIDC090
Cilazapril
Active compound: Cilazaprilat
Indications: Hypertension and heart failure
Target: Angiotensin-converting enzyme (ace)
PDIDC091
Cinazepam
Active compound: 3-Hydroxyphenazepam
Indications: Anxiety, insomnia, muscle spasm, alcohol withdrawal and seizures
Target: Benzodiazepine receptors
PDIDC092
Ciprofloxacin prodrug of stavudine
Active compound: Stavudine
Indications: Tuberculosis
Target: Reverse transcriptase/RnaseH
PDIDC093
Clindamycin palmitate
Active compound: Clindamycin
Indications: Infections due to susceptible strains of streptococci; Prosthetic valve endocarditis
Target: 23S RNA of the 50S subunit of the ribosome
PDIDC094
Clindamycin phosphate
Active compound: Clindamycin
Indications: Gram-positive infections, anaerobic infections, and methicillin-resistant staphlococcal and streptococcal infections
Target: Apurinic/apyrimidinic Endonuclease 1
PDIDC095
ClNH3MeCOO Echinocandin
Active compound: Echinocandin B
Indications: Pneumocystis carinii pneumonia
Target: na
PDIDC096
Clobenzorex
Active compound: D-amphetamine
Indications: Attention deficit hyperactivity disorder (ADHD),obesity and a body mass index (BMI) of 30 kg/m2 or higher who have not responded to an appropriate weight-reducing regimen alone
Target: Sodium-dependent dopamine transporter
PDIDC097
Clofarabine
Active compound: Clofarabine triphosphate
Indications: Relapsed or refractory acute lymphoblastic leukemia
Target: DNA polymerase
PDIDC098
Clofibride
Active compound: clofibric acid
Indications: Obesity complicated with cardiac disorders
Target: na
PDIDC099
Clopidogrel
Active compound: Clopidogrel Thiol Metabolite
Indications: Myocardial infraction, stroke and vascular death
Target: Platelet p2y12 receptor
PDIDC100
Clorazepate
Active compound: Nordazepam
Indications: Epilepsy
Target: GABA-A receptors
PDIDC101
Clostebol acetate
Active compound: Clostebol
Indications: Used as dermatological ointment, Banned performance enhancing drug
Target: na
PDIDC102
Clostebol caproate
Active compound: Clostebol
Indications: Banned performance enhancing drug
Target: na
PDIDC103
Clostebol propionate
Active compound: Clostebol
Indications: Banned performance enhancing drug
Target: na
PDIDC104
Cloxazolam
Active compound: Chlordesmethyldiazepam
Indications: Anxiety, insomnia, muscle spasm, alcohol withdrawal and seizures
Target: Benzodiazepine receptors
PDIDC105
CMX-157
Active compound: Tenofovir
Indications: Hiv infections and chronic hepatitis b
Target: Cellular Reverse Transcriptase inhibitor
PDIDC106
Codeine
Active compound: Morphine
Indications: Pain, Cough, Diarrhea
Target: μ-opioid receptors
PDIDC107
Colistin methanesulfonate
Active compound: Colistin
Indications: Chronic Bacterial infection
Target: Bacterial outer membrane
PDIDC108
Combretastatin A1 bis(phosphate)
Active compound: Combretastatin A1
Indications: Thyroid cancer
Target: Tubulin
PDIDC109
CTK6A1633
Active compound: TAK-456
Indications: Pulmonary aspergillosis
Target: na
PDIDC110
CTK6D3437
Active compound: FTC
Indications: HIV infection
Target: Reverse Transcriptase
PDIDC111
Cyclophosphamide
Active compound: 4-Hydroxy-cyclophosphamide
Indications: Cancers, autoimmune disorders, and al amyloidosis
Target: DNA (alkylating agent)
PDIDC112
Cytarabine ocfosphate
Active compound: Cytarabine triphosphate
Indications: Acute leukaemia
Target: DNA polymerases
PDIDC114
Cytarabine
Active compound: Ara-CTP
Indications: Acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and non-Hodgkin's lymphoma
Target: DNA, DNA Polymerase
PDIDC113
Cladribine
Active compound: Cladribine triphosphate
Indications: Hairy cell leukemia
Target: Na