Showing results for 'T'
Total number of hits: 43
Click on results for more details:
PDIDOTH001
(South)-Methanocarba-Thymidine
Active compound: Thymidine
Indications: Hepatitis b virus (hbv) infection
Target: Thymidine kinase
PDIDOTH012
4-Androstenediol
Active compound: Testosterone
Indications: Stimulates the growth of the prostate as well as the seminal vesicles; Enhance athletic performance
Target: na
PDIDC025
CHEMBL1205526
Active compound: Triapine
Indications: Lung carcinoma
Target: Ribonucleotide reductase
PDIDC037
Chloral hydrate
Active compound: Trichloroethanol
Indications: Sedative-hypnoticdrug
Target: Barbiturate recognition site on GABA-A receptors
PDIDC041
Chlorotrianisene
Active compound: Triphenylethylene
Indications: Hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias
Target: Estrogen receptor
PDIDC105
CMX-157
Active compound: Tenofovir
Indications: Hiv infections and chronic hepatitis b
Target: Cellular Reverse Transcriptase inhibitor
PDIDC109
CTK6A1633
Active compound: TAK-456
Indications: Pulmonary aspergillosis
Target: na
PDIDD005
Dasolampanel
Active compound: Tezampanel
Indications: Migraine
Target: AMPA- and KA-subtype ionotropic Glu receptors
PDIDF025
Fostemsavir
Active compound: Temsavir
Indications: HIV-1
Target: gp120 molecule on Virus surface (Ref 1)
PDIDF028
Fursultiamine
Active compound: Thiamine
Indications: Vitamine B1 deficiency
Target: na
PDIDL007
Leflunomide
Active compound: Teriflunomide
Indications: Rheumatoid arthritis (RA) and psoriatic arthritis
Target: Dihydroorotate dehydrogenase (quinone), mitochondrial
PDIDM021
Minnelide
Active compound: Triptolide
Indications: Pancreatic cancer; Neuroblastoma; Breast cancer; Prostate cancer
Target: ATPase
PDIDM024
Mipsagargin
Active compound: Thapsigargin
Indications: Tumor and Cancer
Target: Prostate-specificmembrane antigen (PSMA)
PDIDR005
Racecadotril
Active compound: Thiorphan
Indications: Acute diarrhea
Target: Neutral endopeptidase/ Enkephalinase
PDIDR018
Romidepsin
Active compound: Thiol derivative of Romidepsin
Indications: Cutaneous T-cell lymphoma (R1)
Target: Histone deacetylases (Ref 1)
PDIDS011
SCHEMBL156939
Active compound: Testosterone
Indications: Osteoporosis, maintain normal muscle and bonemass, erythropoiesis, and sexual function
Target: na
PDIDS024
SCHEMBL5472225
Active compound: Tegafur
Indications: Breast cancer; Lung cancer and Colon cancer
Target: Thymidylate synthase
PDIDS027
SCHEMBL6940322
Active compound: TAK-456
Indications: Aspergillosis
Target: na
PDIDA036
Alatrofloxacin
Active compound: Trovafloxacin
Indications: Broad spectrum antibiotic
Target: DNA gyrase and DNA topoisomerase IV activities
PDIDT002
Tafluprost
Active compound: Tafluprost acid
Indications: Open-angle glaucoma
Target: Prostaglandin f receptor
PDIDT008
Tazarotene
Active compound: Tazarotenic Acid
Indications: Psoriasis, acne, and sun damaged skin
Target: Retinoic acid receptor (rar) family: rarα, rarβ, and rarγ
PDIDT009
Tebipenem-pivoxil
Active compound: Tebipenem
Indications: Otolaryngologic and respiratory infections in pediatric patients
Target: Penicillin-binding proteins (PBPs)
PDIDT010
Tedizolid phosphate
Active compound: Tedizolid
Indications: Acute bacterial skin and skin structure infections (ABSSSIs)
Target: 50S ribosomal subunit
PDIDT014
Telotristat ethyl
Active compound: Telotristat
Indications: Carcinoid syndrome
Target: Tryptophan hydroxylase (tph)
PDIDT015
Telotristat etiprate
Active compound: Telotristat
Indications: Carcinoid syndrome and diarrhea (R1)
Target: Tryptophan hydroxylase [TPH1 and TPH2] (R1, R2)
PDIDT016
Temocapril
Active compound: Temocaprilat
Indications: Hypertension and congestive heart failure, diabetic nephropathy (WL2)
Target: Angiotensin converting enzyme (ACE) (R1)
PDIDT018
Tenofovir alafenamide
Active compound: Tenofovir
Indications: Hepatitis B; HIV-1 infection
Target: Reverse transcriptase/RNaseH; Reverse transcriptase; DNA polymerase (Drug Bank)
PDIDT019
Tenofovir Disoproxil
Active compound: Tenofovir
Indications: HIV/AIDS and hepatitis B
Target: Reverse Transcriptase
PDIDT024
Testosterone palmitate
Active compound: Testosterone
Indications: Na
Target: na
PDIDT025
Testosterone phenylbutyrate
Active compound: Testosterone
Indications: Na
Target: na
PDIDT026
Testosterone stearate
Active compound: Testosterone
Indications: Na
Target: na
PDIDT027
Testosterone undecanoate
Active compound: Testosterone
Indications: Absence or deficiency in endogenous testosterone production
Target: Androgen receptor
PDIDT028
Testosterone valerate
Active compound: Testosterone
Indications: Impotence, weakness, fatigue and hypogonadism in male breeding animals
Target: na
PDIDT030
Ticlopidine
Active compound: Thiol Metabolite of Ticlopidine
Indications: Strokes and coronary stent occlusions
Target: P2Y purinoceptor 12; Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1)
PDIDT037
Trandolapril
Active compound: Trandolaprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDT038
Travoprost
Active compound: Travoprost free acid
Indications: Glaucoma or ocular hypertension
Target: FP prostanoid receptor
PDIDT039
Trenbolone acetate
Active compound: Trenbolone
Indications: To promoting muscle growth in cattle
Target: Androgen receptor (WL1)
PDIDT040
Trenbolone enanthate
Active compound: Trenbolone
Indications: To promoting muscle growth in cattle
Target: Androgen receptor (ref 1)
PDIDT041
Trenbolone hexahydrobenzylcarbonate
Active compound: Trenbolone
Indications: To promoting muscle growth in cattle
Target: Androgen receptor (ref 1)
PDIDT044
Triclofos
Active compound: Trichloroethanol
Indications: Insomnia
Target: na
PDIDT045
TXA709
Active compound: TXA707
Indications: Staphylococcus aureus infection
Target: FtsZ of staphylococcus aurious
PDIDV008
Valtorcitabine
Active compound: Torcitabine triphosphate
Indications: Hepatitis B
Target: HBV polymerase
PDIDB004
Bambuterol
Active compound: Terbutaline
Indications: Asthma, COPD
Target: Beta-2 adrenergic receptor