Showing results for 'P'
Total number of hits: 46
Click on results for more details:
PDIDB016
Bis(3-PentylOC)PMPA
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDB017
Bis(EthylOC)PMPA
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDB018
Bis(NeopentylOC)PMPA
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDB019
Bis(t-ButylOC)PMPA
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDC010
Cbz–Ser–Ser–Phe–Tyr linked prodrug of 4-aminocylophosphamide
Active compound: Phosphoramide mustard
Indications: Prostate cancer
Target: na
PDIDOTH015
4-phenylbutyrate
Active compound: Phenylacetate
Indications: Cystic fibrosis (WL2); hyperammonemia (R1)
Target: Histone deacetylase (WL2)
PDIDC036
CHEMBL62755
Active compound: Phenylmethaneselenol
Indications: Kidney cancer
Target: na
PDIDD023
Dimethylamino parthenolide
Active compound: Parthenolide
Indications: Leukemia and breast cancer
Target: Transcription factor NF-κB.
PDIDD032
Droxicam
Active compound: Piroxicam
Indications: Pain and inflammation
Target: Cyclooxygenase (COX)
PDIDF001
Famciclovir
Active compound: Penciclovir
Indications: Herpesvirus infections; varicella zoster virus (VZV)
Target: DNA polymerase catalytic subunit
PDIDF014
Fmoc-Lys(Ac)-Puromycin
Active compound: Puromycin
Indications: Cancer
Target: 60S ribosomal protein
PDIDF022
Fosphenytoin
Active compound: Phenytoin
Indications: Epilepsy
Target: Sodium channel protein type 5 subunit alpha
PDIDF023
Fospropofol
Active compound: Propofol
Indications: General anesthesia
Target: GABAA receptor
PDIDG006
Glycerol phenylbutyrate
Active compound: Phenylacetate
Indications: Urea cycle disorders (UCDs)
Target: Glutamine
PDIDA019
AC1NUIF5
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDM008
Mericitabine
Active compound: PSI-6130-TP (Metabolite 1)
Indications: Hepatitis C
Target: NS5B HCV RNA-dependent RNA polymerase
PDIDA020
AC1NUIZT
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDM017
Methyl aminolevulinate
Active compound: Protoporphyrin IX
Indications: Actinic keratosis (R1)
Target: High affinity immunoglobulin gamma Fc receptor I (WL2)
PDIDO001
O-Acetylpsilocin
Active compound: Psilocin
Indications: na
Target: na
PDIDP001
P1-185
Active compound: Progesterone
Indications: Traumatic brain injury (TBI)
Target: na
PDIDP002
Paclitaxel docosahexaenoic acid
Active compound: Paclitaxel
Indications: Breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer
Target: Tubulin; Apoptosis regulator Bcl-2 (B-cell Leukemia 2)
PDIDP004
Paliperidone palmitate
Active compound: Paliperidone
Indications: Schizophrenia
Target: Dopamine Type 2 (D2) receptor antagonist and a serotonin Type 2 (5HT2A) receptor antagonist
PDIDP013
Perindopril
Active compound: Perindoprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDP014
Phendimetrazine (PDM)
Active compound: Phenmetrazine
Indications: Stimulant drug, Antisuppressant
Target: Human dopamine transporter
PDIDP021
PR-104
Active compound: PR-104M
Indications: Solid tumors, Lung cancer, And leukemia
Target: DNA
PDIDP022
PR-104A
Active compound: PR-104M
Indications: Solid tumors, Lung cancer, And leukemia
Target: DNA
PDIDP025
Prednisolone phosphate
Active compound: Prednisolone
Indications: Allergic and inflammatory conditions
Target: Glucocorticoid receptor
PDIDP026
Prednisolone tetrahydrophthalate
Active compound: Prednisolone
Indications: Allergic and inflammatory conditions
Target: Glucocorticoid receptor
PDIDP027
Prednisone
Active compound: Prednisolone
Indications: Drug-induced allergic reactions, perennial or seasonal allergic rhinitis, serum sickness, giant cell arteritis acute rheumatic or nonrheumatic carditis, systemic dermatomyositis, systemic lupus erythematosus, atopic dermatitis, contact dermatitis, exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrheic dermatitis, severe (Stevens-Johnson syndrome) erythema multiforme, mycosis fungoides, pemphigus, severe psoriasis, acute adrenocortical insufficiency, Addison's disease, secondary adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with neoplasms, nonsuppurative thyroiditis, ulceratice colitis
Target: Glucocorticoid receptor
PDIDP028
Pregnenolone
Active compound: Pregnenolone sulfate
Indications: Allergic, pruritic, and inflammatory dermatitis
Target: na
PDIDP029
Pregnenolone acetate
Active compound: Pregnenolone
Indications: Rheumatoid arthritis; Nocardiosis
Target: na
PDIDP036
Primidone
Active compound: phenylethylmalonamide (PEMA)
Indications: Partial and generalized seizures
Target: Gamma-aminobutyric acid receptors
PDIDP036
Primidone
Active compound: Phenobarbital
Indications: Partial and generalized seizures
Target: Gamma-aminobutyric acid receptors
PDIDP043
Propacetamol
Active compound: Paracetamol
Indications: Pain and fever
Target: Prostaglandin G/H synthase 1; Cannabinoid receptor 1; Prostaglandin G/H synthase 2
PDIDP045
Psilocybin
Active compound: Psilocin
Indications: Psychological disorder
Target: 5-HT2A, 5-HT2C and 5-HT1A
PDIDP046
Pyrazinamide
Active compound: Pyrazinoic acid
Indications: Tuberculosis
Target: Fatty acid synthase fas i
PDIDP048
Pyridoxine
Active compound: pyridoxal 5-phosphate
Indications: For the treatment of vitamin B6 deficiency and for the prophylaxis of Isoniazid-induced peripheral neuropathy
Target: Pyridoxal kinase
PDIDR015
Risperidone
Active compound: Paliperidone
Indications: Schizophrenia and related disorders
Target: P-glycoprotein-mediated transport; 5-hydroxytryptamine (5-HT)2A, dopamine D2 and α1- and α2-adrenergic receptors
PDIDR017
Rodrigues_etal_1995_PROTAX
Active compound: Paclitaxel
Indications: Breast and ovarian cancers
Target: Tubulin beta-1 chain; Apoptosis regulator Bcl-2; Microtubule-associated protein 4; Microtubule-associated protein 2; Microtubule-associated protein tau
PDIDT003
Taleghani_etal_2017_parthabine
Active compound: Parthenolide
Indications: Cancer
Target: STAT mediated gene transcription and NF-kB mediated gene transcription
PDIDT004
Taleghani_etal_2017_parthalan
Active compound: Parthenolide
Indications: Cancer
Target: STAT mediated gene transcription and NF-kB mediated gene transcription
PDIDV004
Valofan
Active compound: Proxibarbital
Indications: Na
Target: na
PDIDP049
Paclitaxel-2-ethylcarbonate
Active compound: Paclitaxel
Indications: Breast, ovary and lung cancer
Target: Tubulin
PDIDA044
Amfecloral
Active compound: Phenethylamine
Indications: Scizophrenia
Target: Cell system
PDIDA047
Ampiroxicam
Active compound: Piroxicam
Indications: Rheumatoid arthritis and osteoarthritis
Target: Cyclooxygenase (COX)
PDIDB012
Berefrine
Active compound: Phenylephrine
Indications: Indicated to dilate pupils and induce vasoconstriction
Target: Alpha-1A adrenergic receptor; Alpha-1B adrenergic receptor; Alpha-1D adrenergic receptor