Showing results for 'C'
Total number of hits: 49
Click on results for more details:
PDIDB020
Bitolterol
Active compound: Colterol
Indications: Asthma, COPD
Target: β2 adrenergic receptor
PDIDB029
Brincidofovir
Active compound: Cidofovir
Indications: Infection with human cytomegalovirus; Adenovirus
Target: Cytomegalovirus (CMV) DNA Polymerase
PDIDC001
Candesartan Cilexetil
Active compound: Candesartan
Indications: Hypertension
Target: Angiotensin ii receptor
PDIDC002
Candoxatril
Active compound: Candoxatrilat
Indications: heart failure
Target: Neutral endopeptidase and ACE
PDIDC004
Canrenoate
Active compound: Canrenone
Indications: Hypertension (R1)
Target: Mineralocorticoid receptor
PDIDC006
Carfecillin
Active compound: Carbenicillin
Indications: Chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria.
Target: Penicillin binding protein
PDIDC007
Carindacillin
Active compound: Carbenicillin
Indications: Gram-negative bacterial infection
Target: Penicillin-sensitive transpeptidase c-terminal domain
PDIDC013
Cefamandole nafate
Active compound: Cefamandole
Indications: Bacterial Infections
Target: Penicillin-binding protein 2
PDIDC014
Cefcapene pivoxil
Active compound: Cefcapene
Indications: Palmoplantar pustulosis (PPP), Bacterial Infections
Target: Penicillin binding protein
PDIDC015
Cefditoren pivoxil
Active compound: Cefditoren
Indications: Throat and lung infections, including bronchitis and tonsillitis
Target: Penicillin binding protein
PDIDC016
Cefotiam hexetil
Active compound: Cefotiam
Indications: Surgical infection, postoperative infections, bacterial septicaemia, bone and joint infections, cholangitis, cholecystitis, peritonitis, prostatitis, pyelonephritis, respiratory tract infections, skin and soft tissue infections, cystitis, urethritis, and infections caused by susceptible organisms
Target: Penicillin binding protein 1A. 1B and 3 of E. Coli
PDIDC017
Cefpodoxime Proxetil
Active compound: Cefpodoxim
Indications: Gram-positive and Gram-negative bacterial infection
Target: Penicillinases and cephalosporinases
PDIDC018
Ceftaroline Fosamil
Active compound: Ceftaroline
Indications: Acute bacterial skin infections; Community-acquired bacterial pneumonia
Target: Bacterial penicillin-binding protein (ChEMBL)
PDIDC019
Cefteram pivoxil
Active compound: Cefteram
Indications: Laryngopharyngitis,tonsillitis, acute bronchitis, pneumonia, chronic bron-chitis, diffuse panbronchiolitis, infected bronchiec-tasis and other infective chronic respiratory diseases
Target: Penicillin binding protein
PDIDC020
Ceftizoxime alapivoxil
Active compound: Ceftizoxime
Indications: Bacterial Infections
Target: Penicillin binding protein
PDIDC021
Ceftobiprole medocaril
Active compound: Ceftobiprole
Indications: Hospital-acquired pneumonia (HAP) and community-acquired pneumonia (CAP)
Target: Penicillin-binding proteins (PBPs)
PDIDC022
Cefuroxime axetil
Active compound: Cefuroxime
Indications: Bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Target: Penicillin-binding protein 1A
PDIDC023
Cefuroxime pivoxetil
Active compound: Cefuroxime
Indications: Na
Target: Penicillin binding protein
PDIDC024
CEP-7055
Active compound: CEP-5214
Indications: Brain tumors and colon carcinoma
Target: Pan vascular endothelial growthfactors (VEGF) kinase
PDIDC038
Chloramphenicol palmitate
Active compound: Chloramphenicol
Indications: Bacterial infection
Target: 50S ribosomal subunit
PDIDC039
Chloramphenicol stearate
Active compound: Chloramphenicol
Indications: Bacterial infection
Target: 50S ribosomal subunit
PDIDC040
Chloramphenicol succinate
Active compound: Chloramphenicol
Indications: Typhoid fever, salmonella septicaemia
Target: 50S ribosomal subunit
PDIDC089
Cidofovir
Active compound: Cidofovir diphosphate
Indications: Cytomegalovirus (CMV)
Target: Viral DNA
PDIDC090
Cilazapril
Active compound: Cilazaprilat
Indications: Hypertension and heart failure
Target: Angiotensin-converting enzyme (ace)
PDIDC093
Clindamycin palmitate
Active compound: Clindamycin
Indications: Infections due to susceptible strains of streptococci; Prosthetic valve endocarditis
Target: 23S RNA of the 50S subunit of the ribosome
PDIDC094
Clindamycin phosphate
Active compound: Clindamycin
Indications: Gram-positive infections, anaerobic infections, and methicillin-resistant staphlococcal and streptococcal infections
Target: Apurinic/apyrimidinic Endonuclease 1
PDIDC097
Clofarabine
Active compound: Clofarabine triphosphate
Indications: Relapsed or refractory acute lymphoblastic leukemia
Target: DNA polymerase
PDIDC098
Clofibride
Active compound: clofibric acid
Indications: Obesity complicated with cardiac disorders
Target: na
PDIDC099
Clopidogrel
Active compound: Clopidogrel Thiol Metabolite
Indications: Myocardial infraction, stroke and vascular death
Target: Platelet p2y12 receptor
PDIDC101
Clostebol acetate
Active compound: Clostebol
Indications: Used as dermatological ointment, Banned performance enhancing drug
Target: na
PDIDC102
Clostebol caproate
Active compound: Clostebol
Indications: Banned performance enhancing drug
Target: na
PDIDC103
Clostebol propionate
Active compound: Clostebol
Indications: Banned performance enhancing drug
Target: na
PDIDC104
Cloxazolam
Active compound: Chlordesmethyldiazepam
Indications: Anxiety, insomnia, muscle spasm, alcohol withdrawal and seizures
Target: Benzodiazepine receptors
PDIDC107
Colistin methanesulfonate
Active compound: Colistin
Indications: Chronic Bacterial infection
Target: Bacterial outer membrane
PDIDC108
Combretastatin A1 bis(phosphate)
Active compound: Combretastatin A1
Indications: Thyroid cancer
Target: Tubulin
PDIDC112
Cytarabine ocfosphate
Active compound: Cytarabine triphosphate
Indications: Acute leukaemia
Target: DNA polymerases
PDIDD015
DHA-clozapine
Active compound: Clozapine
Indications: Schizophrenia
Target: Dopamine D2 receptor; 5-hydroxytryptamine receptor 2A
PDIDE001
Ebastine
Active compound: Carebastine
Indications: Allergic rhinitis
Target: H1-receptor
PDIDE002
Elacytarabine
Active compound: Cytarabine triphosphate
Indications: Lung cancer, malignant melanoma and ovarian cancer
Target: DNA and RNA synthesis
PDIDE004
Enocitabine
Active compound: Cytarabine triphosphate
Indications: Acute leukaemia
Target: DNA polymerases
PDIDE024
Etofibrate
Active compound: Clofibrate
Indications: Hyperlipidemia
Target: Peroxisome proliferator-activated receptor alpha (KEGG)
PDIDF017
Fosbretabulin
Active compound: Combretastatin A4
Indications: Thyroid cancer
Target: Tubulin
PDIDF018
Fosciclopirox (CPX-POM)
Active compound: Ciclopirox
Indications: Advanced solid tumors
Target: na
PDIDN016
NSC643812
Active compound: Combretastatin
Indications: cancer
Target: Tubulin
PDIDP039
Proguanil
Active compound: Cycloguanil
Indications: Malaria (Plasmodium falciparum and Plasmodium vivax)
Target: Dihydrofolate reductase
PDIDA033
Alacepril
Active compound: Captopril
Indications: Hypertension and congestive heart failure
Target: Angiotensin-converting-enzyme inhibitor
PDIDS039
SN-23862
Active compound: CHEMBL280898
Indications: Tumours
Target: Oxygen-insensitive NAD(P)H nitroreductase
PDIDX002
XMT-1001
Active compound: camptothecin
Indications: Tumor
Target: DNA topoisomerase I
PDIDC113
Cladribine
Active compound: Cladribine triphosphate
Indications: Hairy cell leukemia
Target: Na