Showing results for 'S'
Total number of hits: 51
Click on results for more details:
PDIDS001
Sacubitril
Active compound: Sacubitrilat
Indications: Reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction
Target: Neprilysin (WL1)
PDIDS002
Sarmoxicillin
Active compound: Amoxicillin
Indications: Na
Target: na
PDIDS003
SB 204990
Active compound: SB 201076
Indications: Hypolipidaemia
Target: ATP citrate (pro-S)-lyase
PDIDS004
SCHEMBL10193041
Active compound: SN-38
Indications: Cancer
Target: DNA topoisomerase I inhibitor
PDIDS005
SCHEMBL1068518
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS006
SCHEMBL1069483
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS007
SCHEMBL1070495
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS008
SCHEMBL14377320
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS009
SCHEMBL14764340
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS010
SCHEMBL15272458
Active compound: Afimoxifene
Indications: Breast cancer
Target: Estrogen receptor
PDIDS011
SCHEMBL156939
Active compound: Testosterone
Indications: Osteoporosis, maintain normal muscle and bonemass, erythropoiesis, and sexual function
Target: na
PDIDS012
SCHEMBL18259288
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS013
SCHEMBL18396052
Active compound: ELQ-300
Indications: Malaria
Target: Plasmodium falciparum cytochrome bc1 complex
PDIDS014
SCHEMBL19730390
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDS015
SCHEMBL19730392
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDS016
SCHEMBL19730393
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDS017
SCHEMBL19730395
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDS018
SCHEMBL19730396
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDS019
SCHEMBL19730397
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDS020
SCHEMBL19730398
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDS021
SCHEMBL19730400
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: GABA-benzodiazepine receptor (GABA-BZR) complex
PDIDS022
SCHEMBL4047434
Active compound: Eniluracil
Indications: liver, lung, adrenal, testis, and prostate cancers
Target: Mechanism-based inhibitor of dihy-dropyrimidine dehydrogenase (DPD)
PDIDS023
SCHEMBL4809664
Active compound: Eglumetad
Indications: Psychosis, anxiety, anddrug withdrawal
Target: Group II metabotropic glutamate (mGlu) receptors
PDIDS024
SCHEMBL5472225
Active compound: Tegafur
Indications: Breast cancer; Lung cancer and Colon cancer
Target: Thymidylate synthase
PDIDS025
SCHEMBL6372980
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS026
SCHEMBL6711678
Active compound: 6-Mercaptopurine
Indications: Colon and breast carcinoma
Target: DNA
PDIDS027
SCHEMBL6940322
Active compound: TAK-456
Indications: Aspergillosis
Target: na
PDIDS028
SCHEMBL7441616
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS029
SCHEMBL8504774
Active compound: L014097
Indications: Depression
Target: Non-peptide NK1 neurokinin receptor
PDIDS030
SCHEMBL9356853
Active compound: Dopamine
Indications: Parkinson’s disease (PD)
Target: Dopamine receptor
PDIDS031
Secnidazole
Active compound: Secnidazole active nitro radical
Indications: Bacterial vaginosis in adult women
Target: Bacterial DNA synthesis
PDIDS032
Selexipag
Active compound: MRE-269
Indications: Pulmonary arterial hypertension (PAH); Antithrombotic agents
Target: Prostacyclin Receptor
PDIDS033
Sergliflozin etabonate
Active compound: Sergliflozin
Indications: Type 2 diabetes mellitus (R1)
Target: Sodium-dependent glucose cotransporter 2 (sglt2) (r1)
PDIDS034
SF1126
Active compound: LY294002/SF1101
Indications: Metastatic Solid Tumors / Cancers / Solid Cancers
Target: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
PDIDS035
SF1326
Active compound: LY294002/SF1101
Indications: Metastatic Solid Tumors / Cancers / Solid Cancers
Target: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
PDIDS036
Sibrafiban
Active compound: Ro 44-3888
Indications: Acute coronary syndrome
Target: Fibrinogen receptor; GP IIb-IIIa receptor
PDIDS037
Sibutramine
Active compound: Metabolite 1 (Desmethylsibutramine)
Indications: Obesity (R4)
Target: Sodium-dependent noradrenaline transporter; Sodium-dependent serotonin transporter; Sodium-dependent dopamine transporter
PDIDS037
Sibutramine
Active compound: Metabolite 2
Indications: Obesity (R4)
Target: Sodium-dependent noradrenaline transporter; Sodium-dependent serotonin transporter; Sodium-dependent dopamine transporter
PDIDS038
Simvastatin
Active compound: Simvastatin acid
Indications: Dyslipidemia, elevated lipid levels
Target: 3-hydroxy-3-methylglutaryl (HMG) coenzyme reductase
PDIDS039
SN-23862
Active compound: CHEMBL280898
Indications: Tumours
Target: Oxygen-insensitive NAD(P)H nitroreductase
PDIDS040
SNX-5422
Active compound: SNX-2112
Indications: Breast, lung, and ovarian cancer
Target: Heat shock protein HSP 90
PDIDS041
Sofosbuvir
Active compound: GS-461203
Indications: Hepatitis C
Target: NS5B polymerase
PDIDS042
Spirapril
Active compound: Spiraprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDS043
Spiruchostatin (A)
Active compound: Spiruchostatin A (reduced)
Indications: Breast cancer
Target: Histone deacetylase (HDAC) (R1, R2)
PDIDS044
Stampidine
Active compound: Stavudine
Indications: HIV
Target: Non-nucleoside reverse transcriptase
PDIDS045
Stenbolone acetate
Active compound: Dihydrotestosterone
Indications: Na
Target: Androgen receptor
PDIDS046
Succinylsulfathiazole
Active compound: Sulfathiazole
Indications: Na
Target: Dihydropteroate synthase
PDIDS047
Sulfasalazine
Active compound: 5-aminosalicylic Acid
Indications: Rheumatoid arthritis
Target: Prostaglandin G/H synthase
PDIDS047
Sulfasalazine
Active compound: Sulfapyridine
Indications: Rheumatoid arthritis
Target: Prostaglandin G/H synthase
PDIDS048
Sulindac
Active compound: Sulindac Sulfide
Indications: Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute painful shoulder and acute gouty arthritis
Target: Prostaglandin G/H synthase 2
PDIDS049
Sultamicillin
Active compound: Ampicillin
Indications: Pneumonia and Chronic Obstructive Pulmonary Disease (COPD)
Target: Enzyme transpeptidase