Showing results for 'G'
Total number of hits: 12
Click on results for more details:
PDIDG001
Gabapentin Enacarbil
Active compound: Gabapentin
Indications: Adult Restless Legs Syndrome; postherpetic neuralgia
Target: Voltage-dependent calcium channel subunit alpha-2/delta-1; Voltage-dependent calcium channel subunit alpha-2/delta-2
PDIDG003
Ganciclovir
Active compound: Ganciclovir Triphosphate
Indications: Herpes Simplex Virus infection
Target: DNA polymerase catalytic subunit; viral DNA polymerases; Thymidine kinase
PDIDG004
Gemcitabine
Active compound: Gemcitabin triphosphat (Metabolite 2)
Indications: Ovarian cancer; Metastatic (Stage IV) non-small cell lung cancer; metastatic (Stage IV) adenocarcinoma of the pancreas
Target: DNA
PDIDG004
Gemcitabine
Active compound: Gemcitabine diphosphate (Metabolite 1)
Indications: Ovarian cancer; Breast Cancer
Target: Ribonucleotide reductase
PDIDG009
GS-9131
Active compound: GS-9148-DP
Indications: HIV-1
Target: Nucleoside/Nucleotide Reverse Transcriptase Inhibitors
PDIDG010
GW5634
Active compound: GW8248
Indications: HIV infection
Target: HIV-1 non-nucleoside reversetranscriptase inhibitors (NNRTIs)
PDIDA021
Aceburic acid
Active compound: Gamma-hydroxybutyrate
Indications: Anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance.
Target: Cell specific
PDIDP016
Picamilon
Active compound: GABA
Indications: Migraine, neuro infections, senile psychosis, certain types of glaucoma, and even acute alcohol intoxication
Target: GABA-A and GABA-B
PDIDS041
Sofosbuvir
Active compound: GS-461203
Indications: Hepatitis C
Target: NS5B polymerase
PDIDT013
Teglarinad
Active compound: GMX1778
Indications: Chronic lymphocytic leukemia, acute leukemia,and high-grade lymphomas
Target: Nicotinamide phosphoribosyl transferase
PDIDT034
Tolgabide
Active compound: GABA
Indications: Epilepsy
Target: GABA receptor (WL1)
PDIDV003
Valganciclovir
Active compound: Ganciclovir
Indications: Cytomegalovirus infections
Target: DNA polymerase, Thymidine kinase of HHV1