Showing results for 'P'
Total number of hits: 50
Click on results for more details:
PDIDP001
P1-185
Active compound: Progesterone
Indications: Traumatic brain injury (TBI)
Target: na
PDIDP002
Paclitaxel docosahexaenoic acid
Active compound: Paclitaxel
Indications: Breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer
Target: Tubulin; Apoptosis regulator Bcl-2 (B-cell Leukemia 2)
PDIDP003
Pafuramidine
Active compound: Furamidine
Indications: Pneumocystis pneumonia
Target: na
PDIDP004
Paliperidone palmitate
Active compound: Paliperidone
Indications: Schizophrenia
Target: Dopamine Type 2 (D2) receptor antagonist and a serotonin Type 2 (5HT2A) receptor antagonist
PDIDP005
Pantoprazole
Active compound: Sulfenamide form of Pantoprazole
Indications: Erosive esophagitis associated with gastroesophageal reflux disease (gerd)
Target: (H+,K+)-ATPase
PDIDP006
Paracetamol
Active compound: N-arachidonoylphenolamine
Indications: Pain and fever.
Target: Cyclooxygenase (COX), TRPA1-receptors
PDIDP007
Parecoxib
Active compound: Valdecoxib
Indications: Antiinflammatory; To reduce post-operative pain
Target: Cyclooxygenase-2 (COX-2)
PDIDP008
PBBG (Pyrrolo[2,1-c][1,4]-benzodiazepine-beta-glucuronide)
Active compound: NSC718813
Indications: Solid tumors
Target: DNA minor groove
PDIDP009
PD1
Active compound: Levofloxacin
Indications: Acute bacterial sinusitis, pneumonia, urinary tract infections, chronic prostatitis, traveler's diarrhea, tuberculosis, and plague and some types of gastroenteritis
Target: Cell specific
PDIDP010
PD2
Active compound: Levofloxacin
Indications: Urinary tract infection and Pneumonia
Target: Cell specific
PDIDP011
Penethamate
Active compound: Benzylpenicillin
Indications: Na
Target: na
PDIDP012
Peptide-doxorubicin prodrug
Active compound: Doxorubicin
Indications: Tumor
Target: na
PDIDP013
Perindopril
Active compound: Perindoprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDP014
Phendimetrazine (PDM)
Active compound: Phenmetrazine
Indications: Stimulant drug, Antisuppressant
Target: Human dopamine transporter
PDIDP015
Phthalylsulfathiazole
Active compound: Sulfathiazole
Indications: Na
Target: Dihydropteroate synthase
PDIDP016
Picamilon
Active compound: GABA
Indications: Migraine, neuro infections, senile psychosis, certain types of glaucoma, and even acute alcohol intoxication
Target: GABA-A and GABA-B
PDIDP017
Piperazine prodrug of Stavudine
Active compound: Stavudine
Indications: HIV/AIDS
Target: Reverse transcriptase/RnaseH
PDIDP018
Pivampicillin
Active compound: Ampicillin
Indications: Respiratory tract infections; Ear, nose and throat infections; Gynecological infections; Urinary tract infections
Target: Enzyme transpeptidase
PDIDP019
Pivmecillinam
Active compound: Mecillinam
Indications: Urinary tract infections, salmonellosis and typhoid fever (WL1)
Target: Penicillin-binding protein 1A
PDIDP020
Polyestradiol phosphate
Active compound: Estradiol
Indications: Prostatic cancer
Target: Estrogen receptor alpha
PDIDP021
PR-104
Active compound: PR-104M
Indications: Solid tumors, Lung cancer, And leukemia
Target: DNA
PDIDP022
PR-104A
Active compound: PR-104M
Indications: Solid tumors, Lung cancer, And leukemia
Target: DNA
PDIDP023
Pradefovir
Active compound: Adefovir
Indications: Hepatitis B
Target: Adevofir diphosphate inhibition of RNA-dependent DNA polymerase (By competing with natural dATPs)
PDIDP024
Prasugrel
Active compound: R-138727
Indications: Acute Coronary Syndrome (ACS); unstable angina (UA); non-ST elevation myocardial infarction (NSTEMI); ST-elevation myocardial infarction (STEMI)
Target: ADP receptor
PDIDP025
Prednisolone phosphate
Active compound: Prednisolone
Indications: Allergic and inflammatory conditions
Target: Glucocorticoid receptor
PDIDP026
Prednisolone tetrahydrophthalate
Active compound: Prednisolone
Indications: Allergic and inflammatory conditions
Target: Glucocorticoid receptor
PDIDP027
Prednisone
Active compound: Prednisolone
Indications: Drug-induced allergic reactions, perennial or seasonal allergic rhinitis, serum sickness, giant cell arteritis acute rheumatic or nonrheumatic carditis, systemic dermatomyositis, systemic lupus erythematosus, atopic dermatitis, contact dermatitis, exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrheic dermatitis, severe (Stevens-Johnson syndrome) erythema multiforme, mycosis fungoides, pemphigus, severe psoriasis, acute adrenocortical insufficiency, Addison's disease, secondary adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with neoplasms, nonsuppurative thyroiditis, ulceratice colitis
Target: Glucocorticoid receptor
PDIDP028
Pregnenolone
Active compound: Pregnenolone sulfate
Indications: Allergic, pruritic, and inflammatory dermatitis
Target: na
PDIDP029
Pregnenolone acetate
Active compound: Pregnenolone
Indications: Rheumatoid arthritis; Nocardiosis
Target: na
PDIDP030
Pretomanid
Active compound: (S)-des nitro PA-824
Indications: Multidrug-resistant (MDR), extensively drug-resistant (XDR), and treatment-intolerant forms of pulmonary tuberculosis (TB)
Target: Mycolic acid biosynthesis
PDIDP031
Prexenocoumacin A
Active compound: Xenocoumacin 1
Indications: Bacterial Infections
Target: na
PDIDP032
Prexenocoumacin B
Active compound: Xenocoumacin 1
Indications: Bacterial Infections
Target: na
PDIDP033
Prexenocoumacin C
Active compound: Xenocoumacin 1
Indications: Bacterial Infections
Target: na
PDIDP034
Prexenocoumacin D
Active compound: Xenocoumacin 1
Indications: Bacterial Infections
Target: na
PDIDP035
Prexenocoumacin E
Active compound: Xenocoumacin 1
Indications: Bacterial Infections
Target: na
PDIDP036
Primidone
Active compound: phenylethylmalonamide (PEMA)
Indications: Partial and generalized seizures
Target: Gamma-aminobutyric acid receptors
PDIDP036
Primidone
Active compound: Phenobarbital
Indications: Partial and generalized seizures
Target: Gamma-aminobutyric acid receptors
PDIDP037
Procarbazine
Active compound: Azoprocarbazine
Indications: Brain tumors and Hodgkin's lymphoma
Target: DNA (alkylating agent)
PDIDP038
Progabide
Active compound: SL-75102
Indications: Epilepsy
Target: GABAA, GABAB, and GABAA-ρ receptors
PDIDP039
Proguanil
Active compound: Cycloguanil
Indications: Malaria (Plasmodium falciparum and Plasmodium vivax)
Target: Dihydrofolate reductase
PDIDP040
ProINDY
Active compound: INDY
Indications: Down syndrome
Target: Dual-specificity tyrosine-(y)-phosphorylation-regulated kinase 1a
PDIDP041
Promitil
Active compound: Mitomycin C
Indications: Liver, Lung and kidney Cancer
Target: DNA
PDIDP042
Prontosil
Active compound: Sulfanilamide
Indications: Erysipelas (R1)
Target: Dihydropteroate synthase
PDIDP043
Propacetamol
Active compound: Paracetamol
Indications: Pain and fever
Target: Prostaglandin G/H synthase 1; Cannabinoid receptor 1; Prostaglandin G/H synthase 2
PDIDP044
Prulifloxacin
Active compound: Ulifloxacin
Indications: Chronic bronchitis, uncomplicated and complicated urinary tract infections, and chronic bacterial prostatitis
Target: Bacterial dna gyrase
PDIDP045
Psilocybin
Active compound: Psilocin
Indications: Psychological disorder
Target: 5-HT2A, 5-HT2C and 5-HT1A
PDIDP046
Pyrazinamide
Active compound: Pyrazinoic acid
Indications: Tuberculosis
Target: Fatty acid synthase fas i
PDIDP047
pyrazinamide prodrug of stavudine
Active compound: Stavudine
Indications: Tuberculosis
Target: Reverse transcriptase/RnaseH
PDIDP048
Pyridoxine
Active compound: pyridoxal 5-phosphate
Indications: For the treatment of vitamin B6 deficiency and for the prophylaxis of Isoniazid-induced peripheral neuropathy
Target: Pyridoxal kinase
PDIDP049
Paclitaxel-2-ethylcarbonate
Active compound: Paclitaxel
Indications: Breast, ovary and lung cancer
Target: Tubulin