Showing results for 'I'
Total number of hits: 14
Click on results for more details:
PDIDI001
Ibotenic acid
Active compound: Muscimol
Indications: Na
Target: GABAA and GABAC
PDIDI002
Ibuprofen piconol
Active compound: Ibuprofen
Indications: Pain and inflammation; atopic dermatitis
Target: Prostaglandin-endoperoxide synthase 1 and prostaglandin-endoperoxide synthase 2 (KEGG)
PDIDI003
Ifosfamide
Active compound: 4-hydroxyifosfamide
Indications: Cancer
Target: DNA
PDIDI004
Imidapril
Active compound: Imidaprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDI005
Imipramine
Active compound: Desipramine
Indications: Depression
Target: Noradrenaline transporter (NET) reuptake inhibitor
PDIDI006
Indomethacin farnesil
Active compound: Indomethacin
Indications: Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Bursitis, Osteoarthritis (OA), Pain (Acute), Patent Ductus Arteriosus (PDA), Rheumatoid Arthritis, Tendinitis (DrugBank)
Target: Prostaglandin-endoperoxide synthase 1 and prostaglandin-endoperoxide synthase 2 (KEGG)
PDIDI007
Irinotecan (CPT-11)
Active compound: 7-ethyl-10-hydroxycamptothecin
Indications: Colon cancer
Target: Topoisomerase I
PDIDI008
Isavuconazonium
Active compound: Isavuconazole
Indications: Invasive aspergillosis and Invasive mucormycosis
Target: lanosterol 14-alpha-demethylase (Ref 1); cytochrome P450 3A4 (CYP3A4/5) (Ref 2)
PDIDI009
Isoniazid
Active compound: Isonicotinic Acyl redical
Indications: Tuberculosis (TB)
Target: Enoyl-acyl carrier protein reductase (inha); Catalase-peroxidase
PDIDI010
Isoniazide prodrug of stavudine
Active compound: Stavudine
Indications: Tuberculosis
Target: Reverse transcriptase/RnaseH
PDIDI011
Isosorbide Diaspirinate
Active compound: Aspirin
Indications: Pain, fever, and inflammation; To inhibit platelet aggregation; myocardial infarction (MI); transient ischemic attacks (TIA); For the prevention of thromboembolism; coronary artery disease (CAD)
Target: Prostaglandin G/H synthase 1; Prostaglandin G/H synthase 2
PDIDI012
Isosorbide nitroaspirin
Active compound: Aspirin
Indications: Pain, fever, and inflammation; To inhibit platelet aggregation; myocardial infarction (MI); transient ischemic attacks (TIA); For the prevention of thromboembolism; coronary artery disease (CAD)
Target: Prostaglandin G/H synthase 1; Prostaglandin G/H synthase 2
PDIDI013
Isoxazolyl-prodrug of distamycin
Active compound: Distamycin
Indications: Na
Target: DNA topoisomerase 1; Estrogen receptor; GTPase Hras (WL1)
PDIDI014
Ixazomib citrate
Active compound: Ixazomib
Indications: Multiple Myeloma (MM)
Target: 20S proteasome