Showing results for 'Lipophilicity'
Total number of hits: 59
Click on results for more details:
PDIDB016
Bis(3-PentylOC)PMPA
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDB017
Bis(EthylOC)PMPA
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDB018
Bis(NeopentylOC)PMPA
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDB019
Bis(t-ButylOC)PMPA
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDC016
Cefotiam hexetil
Active compound: Cefotiam
Indications: Surgical infection, postoperative infections, bacterial septicaemia, bone and joint infections, cholangitis, cholecystitis, peritonitis, prostatitis, pyelonephritis, respiratory tract infections, skin and soft tissue infections, cystitis, urethritis, and infections caused by susceptible organisms
Target: Penicillin binding protein 1A. 1B and 3 of E. Coli
PDIDC020
Ceftizoxime alapivoxil
Active compound: Ceftizoxime
Indications: Bacterial Infections
Target: Penicillin binding protein
PDIDC022
Cefuroxime axetil
Active compound: Cefuroxime
Indications: Bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Target: Penicillin-binding protein 1A
PDIDC039
Chloramphenicol stearate
Active compound: Chloramphenicol
Indications: Bacterial infection
Target: 50S ribosomal subunit
PDIDC093
Clindamycin palmitate
Active compound: Clindamycin
Indications: Infections due to susceptible strains of streptococci; Prosthetic valve endocarditis
Target: 23S RNA of the 50S subunit of the ribosome
PDIDC106
Codeine
Active compound: Morphine
Indications: Pain, Cough, Diarrhea
Target: μ-opioid receptors
PDIDC110
CTK6D3437
Active compound: FTC
Indications: HIV infection
Target: Reverse Transcriptase
PDIDD013
Dexrazoxane
Active compound: ADR-925
Indications: Cardiomyopathy
Target: Topoisomerase II
PDIDE002
Elacytarabine
Active compound: Cytarabine triphosphate
Indications: Lung cancer, malignant melanoma and ovarian cancer
Target: DNA and RNA synthesis
PDIDE012
Estradiol benzoate
Active compound: Estradiol
Indications: Terminate pregnancy; Menstrual disorder; Prostate cancer
Target: Estrogen Receptor (ER) including ERα and ERβ subtypes
PDIDE013
Estradiol cypionate
Active compound: Estradiol
Indications: Moderate to severe vasomotor symptoms associated with menopause; Hypoestrogenism due to hypogonadism
Target: Estrogen Receptor (ER) including ERα and ERβ subtypes; NR3A (ESR)(KEGG)
PDIDH002
Heroin
Active compound: Morphine
Indications: Pain
Target: μ-opioid receptors
PDIDI006
Indomethacin farnesil
Active compound: Indomethacin
Indications: Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Bursitis, Osteoarthritis (OA), Pain (Acute), Patent Ductus Arteriosus (PDA), Rheumatoid Arthritis, Tendinitis (DrugBank)
Target: Prostaglandin-endoperoxide synthase 1 and prostaglandin-endoperoxide synthase 2 (KEGG)
PDIDK002
KP-1461
Active compound: KP-1212
Indications: HIV infection
Target: Reverse Transcriptase
PDIDL005
Latanoprost
Active compound: Latanoprost acid
Indications: Open-angle glaucoma or ocular hypertension; intraocular pressure as a result of angle-closure glaucoma
Target: Prostaglandin F2-alpha receptor
PDIDL008
Lefradafiban
Active compound: Fradafiban
Indications: Angina
Target: Human platelet GP IIb/IIIa complex
PDIDL010
Levacetylmethadol
Active compound: Levo-alpha-acetyl-N-normethadol
Indications: Opioid dependence
Target: μ-opioid receptors
PDIDA018
AC1MHEO9
Active compound: 2-Amino-6-methoxypurine analogue
Indications: Cytomegalo Virus Infection
Target: DNA
PDIDA019
AC1NUIF5
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDM010
Mestilbol
Active compound: Diethylstilbestrol
Indications: Menopause
Target: Estrogen receptor
PDIDA020
AC1NUIZT
Active compound: PMPA
Indications: HIV infection
Target: Reverse Transcriptase
PDIDM017
Methyl aminolevulinate
Active compound: Protoporphyrin IX
Indications: Actinic keratosis (R1)
Target: High affinity immunoglobulin gamma Fc receptor I (WL2)
PDIDM027
Moexipril
Active compound: Moexiprilat
Indications: Hypertension and congestive heart failure
Target: Angiotensin-converting-enzyme
PDIDN007
Nicomorphine
Active compound: Morphine
Indications: Na
Target: mu-type opioid receptor
PDIDO009
Oxcarbazepine
Active compound: Licarbazepine
Indications: Partial seizures in children and adults with epilepsy; Diabetic Peripheral Neuropathic Pain (DPN)
Target: Sodium channel protein type 5 subunit alpha
PDIDP009
PD1
Active compound: Levofloxacin
Indications: Acute bacterial sinusitis, pneumonia, urinary tract infections, chronic prostatitis, traveler's diarrhea, tuberculosis, and plague and some types of gastroenteritis
Target: Cell specific
PDIDP010
PD2
Active compound: Levofloxacin
Indications: Urinary tract infection and Pneumonia
Target: Cell specific
PDIDP013
Perindopril
Active compound: Perindoprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDP015
Phthalylsulfathiazole
Active compound: Sulfathiazole
Indications: Na
Target: Dihydropteroate synthase
PDIDP018
Pivampicillin
Active compound: Ampicillin
Indications: Respiratory tract infections; Ear, nose and throat infections; Gynecological infections; Urinary tract infections
Target: Enzyme transpeptidase
PDIDP044
Prulifloxacin
Active compound: Ulifloxacin
Indications: Chronic bronchitis, uncomplicated and complicated urinary tract infections, and chronic bacterial prostatitis
Target: Bacterial dna gyrase
PDIDQ002
Quinapril
Active compound: Quinaprilat
Indications: Hypertension and congestive heart failure
Target: Angiotensin-converting-enzyme
PDIDR006
Ramipril
Active compound: Ramiprilat
Indications: Hypertension and congestive heart failure
Target: Angiotensin-converting-enzyme
PDIDR011
Resolvin D2 Methyl Ester
Active compound: Resolvin free acid
Indications: Cronic Inflamation
Target: FPR2 and GPR32 types of G-Protein-coupled receptors
PDIDR015
Risperidone
Active compound: Paliperidone
Indications: Schizophrenia and related disorders
Target: P-glycoprotein-mediated transport; 5-hydroxytryptamine (5-HT)2A, dopamine D2 and α1- and α2-adrenergic receptors
PDIDS002
Sarmoxicillin
Active compound: Amoxicillin
Indications: Na
Target: na
PDIDS038
Simvastatin
Active compound: Simvastatin acid
Indications: Dyslipidemia, elevated lipid levels
Target: 3-hydroxy-3-methylglutaryl (HMG) coenzyme reductase
PDIDS042
Spirapril
Active compound: Spiraprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDS046
Succinylsulfathiazole
Active compound: Sulfathiazole
Indications: Na
Target: Dihydropteroate synthase
PDIDT002
Tafluprost
Active compound: Tafluprost acid
Indications: Open-angle glaucoma
Target: Prostaglandin f receptor
PDIDT008
Tazarotene
Active compound: Tazarotenic Acid
Indications: Psoriasis, acne, and sun damaged skin
Target: Retinoic acid receptor (rar) family: rarα, rarβ, and rarγ
PDIDT020
Terfenadine
Active compound: Fexofenadine
Indications: Allergic rhinitis, hay fever, and allergic skin disorders (WL2)
Target: Histamine H1 receptor
PDIDT024
Testosterone palmitate
Active compound: Testosterone
Indications: Na
Target: na
PDIDT026
Testosterone stearate
Active compound: Testosterone
Indications: Na
Target: na
PDIDT028
Testosterone valerate
Active compound: Testosterone
Indications: Impotence, weakness, fatigue and hypogonadism in male breeding animals
Target: na
PDIDT031
Tilidine
Active compound: Bisnortilidin
Indications: Pain
Target: μ-opioid receptors
PDIDT031
Tilidine
Active compound: Nortilidine
Indications: Pain
Target: μ-opioid receptors
PDIDT037
Trandolapril
Active compound: Trandolaprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDT046
Tybamate
Active compound: Meprobamate
Indications: Chronic brain syndrome (R2); anxiety disorders (WL1)
Target: na
PDIDV004
Valofan
Active compound: Proxibarbital
Indications: Na
Target: na
PDIDZ002
Zofenopril
Active compound: Zofenoprilat
Indications: Hypertension, congestive heart failure, acute myocardial infarction, and diabetic nephropathy (R 1)
Target: Angiotensin-Converting Enzyme (ACE) (R 1, WL 3) ; peptidyl-dipeptidase A (WL 2)
PDIDA048
AN-9
Active compound: Butyric acid
Indications: Liver cancer, lung cancer, melanoma, and leukemia
Target: Histone deacetylase
PDIDB004
Bambuterol
Active compound: Terbutaline
Indications: Asthma, COPD
Target: Beta-2 adrenergic receptor
PDIDB011
Benzphetamine
Active compound: d-Amphetamine
Indications: Attention deficit hyperactivity disorder (ADHD)
Target: Sodium-dependent dopamine transporter; Synaptic vesicular amine transporter
PDIDB012
Berefrine
Active compound: Phenylephrine
Indications: Indicated to dilate pupils and induce vasoconstriction
Target: Alpha-1A adrenergic receptor; Alpha-1B adrenergic receptor; Alpha-1D adrenergic receptor