Showing results for 'T'
Total number of hits: 48
Click on results for more details:
PDIDT001
TAFA-93
Active compound: Rapamycin
Indications: Transplant (Rejection); Autoimmune and oncological diseases
Target: mTOR
PDIDT002
Tafluprost
Active compound: Tafluprost acid
Indications: Open-angle glaucoma
Target: Prostaglandin f receptor
PDIDT003
Taleghani_etal_2017_parthabine
Active compound: Parthenolide
Indications: Cancer
Target: STAT mediated gene transcription and NF-kB mediated gene transcription
PDIDT004
Taleghani_etal_2017_parthalan
Active compound: Parthenolide
Indications: Cancer
Target: STAT mediated gene transcription and NF-kB mediated gene transcription
PDIDT005
Talniflumate
Active compound: Niflumic acid
Indications: Rheumatoid arthritis and osteoarthritis
Target: Chloride channel protein ClC-Ka; Prostaglandin G/H synthase 1; Prostaglandin G/H synthase 2
PDIDT006
Tamoxifen
Active compound: Afimoxifene
Indications: Breast cancer
Target: Estrogen receptor
PDIDT006
Tamoxifen
Active compound: Endoxifen
Indications: Breast cancer
Target: Estrogen receptor
PDIDT007
Taribavirin
Active compound: Ribavirin
Indications: Hepatitis C (WL1, R2)
Target: RNA-directed RNA polymerase catalytic subunit; Cytosolic purine 5'-nucleotidase; Inosine-5'-monophosphate dehydrogenase 1 (WL1)
PDIDT008
Tazarotene
Active compound: Tazarotenic Acid
Indications: Psoriasis, acne, and sun damaged skin
Target: Retinoic acid receptor (rar) family: rarα, rarβ, and rarγ
PDIDT009
Tebipenem-pivoxil
Active compound: Tebipenem
Indications: Otolaryngologic and respiratory infections in pediatric patients
Target: Penicillin-binding proteins (PBPs)
PDIDT010
Tedizolid phosphate
Active compound: Tedizolid
Indications: Acute bacterial skin and skin structure infections (ABSSSIs)
Target: 50S ribosomal subunit
PDIDT012
Tegafur
Active compound: 5-Fluorouracil
Indications: Candida or Cryptococcus neoformans fungal infections
Target: Thymidylate Synthase (TS)
PDIDT013
Teglarinad
Active compound: GMX1778
Indications: Chronic lymphocytic leukemia, acute leukemia,and high-grade lymphomas
Target: Nicotinamide phosphoribosyl transferase
PDIDT014
Telotristat ethyl
Active compound: Telotristat
Indications: Carcinoid syndrome
Target: Tryptophan hydroxylase (tph)
PDIDT015
Telotristat etiprate
Active compound: Telotristat
Indications: Carcinoid syndrome and diarrhea (R1)
Target: Tryptophan hydroxylase [TPH1 and TPH2] (R1, R2)
PDIDT016
Temocapril
Active compound: Temocaprilat
Indications: Hypertension and congestive heart failure, diabetic nephropathy (WL2)
Target: Angiotensin converting enzyme (ACE) (R1)
PDIDT017
Temozolomide
Active compound: 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC)
Indications: Brain cancers, astrocytoma, glioblastoma multiforme
Target: DNA (alkylating agent)
PDIDT018
Tenofovir alafenamide
Active compound: Tenofovir
Indications: Hepatitis B; HIV-1 infection
Target: Reverse transcriptase/RNaseH; Reverse transcriptase; DNA polymerase (Drug Bank)
PDIDT019
Tenofovir Disoproxil
Active compound: Tenofovir
Indications: HIV/AIDS and hepatitis B
Target: Reverse Transcriptase
PDIDT020
Terfenadine
Active compound: Fexofenadine
Indications: Allergic rhinitis, hay fever, and allergic skin disorders (WL2)
Target: Histamine H1 receptor
PDIDT021
Terlipressin
Active compound: Lysine vasopressin
Indications: Sepsis-associated arterial hypotension
Target: Vasopressin V1a receptor
PDIDT022
Testifenon
Active compound: Dihydrotestosterone
Indications: Tumor and Cancer
Target: Androgen receptor
PDIDT023
Testosterone
Active compound: 5-dihydrotestosterone (DHT)
Indications: Primary hypogonadism and hypogonadotropic hypogonadism
Target: Androgen receptor
PDIDT024
Testosterone palmitate
Active compound: Testosterone
Indications: Na
Target: na
PDIDT025
Testosterone phenylbutyrate
Active compound: Testosterone
Indications: Na
Target: na
PDIDT026
Testosterone stearate
Active compound: Testosterone
Indications: Na
Target: na
PDIDT027
Testosterone undecanoate
Active compound: Testosterone
Indications: Absence or deficiency in endogenous testosterone production
Target: Androgen receptor
PDIDT028
Testosterone valerate
Active compound: Testosterone
Indications: Impotence, weakness, fatigue and hypogonadism in male breeding animals
Target: na
PDIDT029
Thymectacin
Active compound: Brivudine monophosphate
Indications: Tumours
Target: Thymidylate synthase (ts)
PDIDT029
Thymectacin
Active compound: Brivudine
Indications: Colorectal cancer
Target: Thymidylate synthase
PDIDT030
Ticlopidine
Active compound: Thiol Metabolite of Ticlopidine
Indications: Strokes and coronary stent occlusions
Target: P2Y purinoceptor 12; Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1)
PDIDT031
Tilidine
Active compound: Bisnortilidin
Indications: Pain
Target: μ-opioid receptors
PDIDT031
Tilidine
Active compound: Nortilidine
Indications: Pain
Target: μ-opioid receptors
PDIDT032
Tinidazole
Active compound: Metronidazole
Indications: Bacterial vaginosis (BV); giardiasis and amoebiasis
Target: DNA
PDIDT033
Tirapazamine
Active compound: Benzotriazinyl radicals
Indications: Breast and lung cancer
Target: DNA minor grove
PDIDT034
Tolgabide
Active compound: GABA
Indications: Epilepsy
Target: GABA receptor (WL1)
PDIDT035
Tolterodine
Active compound: 5-Hydroxymethyltolterodine (5-HMT)
Indications: Urinary incontinence
Target: M2 and M3 muscarinic receptors
PDIDT036
Tramadol
Active compound: O-Demethyltramadol
Indications: Acute and chronic pain
Target: μ-opioid receptors
PDIDT037
Trandolapril
Active compound: Trandolaprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDT038
Travoprost
Active compound: Travoprost free acid
Indications: Glaucoma or ocular hypertension
Target: FP prostanoid receptor
PDIDT039
Trenbolone acetate
Active compound: Trenbolone
Indications: To promoting muscle growth in cattle
Target: Androgen receptor (WL1)
PDIDT040
Trenbolone enanthate
Active compound: Trenbolone
Indications: To promoting muscle growth in cattle
Target: Androgen receptor (ref 1)
PDIDT041
Trenbolone hexahydrobenzylcarbonate
Active compound: Trenbolone
Indications: To promoting muscle growth in cattle
Target: Androgen receptor (ref 1)
PDIDT042
Trestolone acetate
Active compound: 19-nortestosterone
Indications: To promoting muscle growth in cattle
Target: Androgen receptor; progesterone receptor (ref 1)
PDIDT043
Tretazicar
Active compound: 5-(aziridin-1-yl)-4-acetoxy-2-nitrobenzamide
Indications: Tumours
Target: DNA
PDIDT044
Triclofos
Active compound: Trichloroethanol
Indications: Insomnia
Target: na
PDIDT045
TXA709
Active compound: TXA707
Indications: Staphylococcus aureus infection
Target: FtsZ of staphylococcus aurious
PDIDT046
Tybamate
Active compound: Meprobamate
Indications: Chronic brain syndrome (R2); anxiety disorders (WL1)
Target: na