Showing results for 'M'
Total number of hits: 31
Click on results for more details:
PDIDM001
MB07133
Active compound: Ara-CMP
Indications: Myelodysplastic Syndrome; Leukemia; Hepatocellular carcinoma (HCC); liver cancer
Target: AraC triphosphate (araCTP) inhibition of DNA polymerase (By competing with cytidine)
PDIDM002
MB07811
Active compound: MB07344
Indications: Hyperlipidemia
Target: Thyroid hormone receptor beta
PDIDM003
Mebolazine
Active compound: Methasterone
Indications: Na
Target: na
PDIDM004
Melevodopa
Active compound: Levodopa
Indications: Parkinson’s disease (R2, R3)
Target: Dopamine receptors
PDIDM005
Menadione
Active compound: Semiquinone radical
Indications: iver, colon, lung, stomach, and prostateand leukemia
Target: DNA
PDIDM006
MeP-dR
Active compound: 6-Methylpurine
Indications: Tumors
Target: Purine nucleoside phosphorylase DeoD-type
PDIDM007
Mepitiostane
Active compound: Epitiostanol
Indications: Breast cancer
Target: Estrogen receptor alpha; Estrogen receptor beta
PDIDM008
Mericitabine
Active compound: PSI-6130-TP (Metabolite 1)
Indications: Hepatitis C
Target: NS5B HCV RNA-dependent RNA polymerase
PDIDM008
Mericitabine
Active compound: Uridine-triphosphate (Metabolite 2)
Indications: Hepatitis C
Target: NS5B HCV RNA-dependent RNA polymerase
PDIDM009
Mesocarb
Active compound: Amphetamine
Indications: Parkinson’s disease (WL1)
Target: na
PDIDM010
Mestilbol
Active compound: Diethylstilbestrol
Indications: Menopause
Target: Estrogen receptor
PDIDM011
Mestranol
Active compound: Ethinyl estradiol
Indications: Oral contraceptives
Target: Estrogen receptor alpha (WL1, WL2); estrogen receptor beta (WL2)
PDIDM012
Metenolone enanthate
Active compound: Metenolone
Indications: Anemia (WL1)
Target: Androgen receptor (WL2)
PDIDM013
Methandriol bisenanthoyl acetate
Active compound: Methandriol
Indications: Na
Target: na
PDIDM014
Methandriol diacetate
Active compound: Methandriol
Indications: Na
Target: na
PDIDM015
Methandriol dipropionate
Active compound: Methandriol
Indications: Na
Target: Androgen receptor (WL1)
PDIDM016
Methandriol propionate
Active compound: Methandriol
Indications: Na
Target: na
PDIDM017
Methyl aminolevulinate
Active compound: Protoporphyrin IX
Indications: Actinic keratosis (R1)
Target: High affinity immunoglobulin gamma Fc receptor I (WL2)
PDIDM018
Metrifonate
Active compound: 2,2-dichlorovinyl Dimethyl Phosphate (DDVP)
Indications: Schistosomiasis; Alzheimer’s disease
Target: Acetylcholinesterase (AChE)
PDIDM019
Mevastatin
Active compound: Hydroxy acid form of Mevastatin
Indications: Bacterial Infections
Target: HMG-CoA reductase
PDIDM020
Midodrine
Active compound: Desglymidodrine (DMAE)
Indications: Dysautonomia and orthostatic hypotension
Target: Alpha-adrenergic receptors
PDIDM021
Minnelide
Active compound: Triptolide
Indications: Pancreatic cancer; Neuroblastoma; Breast cancer; Prostate cancer
Target: ATPase
PDIDM022
Minoxidil
Active compound: Minoxidil sulphate
Indications: Androgenetic alopecia (AGA)
Target: ATP-sensitive inward rectifier potassium channel 1
PDIDM023
Miproxifene phosphate
Active compound: Miproxifene
Indications: Breast cancer (Ref 1)
Target: Estrogen receptor (ER) (R1)
PDIDM024
Mipsagargin
Active compound: Thapsigargin
Indications: Tumor and Cancer
Target: Prostate-specificmembrane antigen (PSMA)
PDIDM025
Mitomycin C
Active compound: Quinone Methide
Indications: Breast, stomach, esophagus, bladder and non-small cell lung cancer
Target: DNA minor grove
PDIDM026
MLN9708
Active compound: Ixazomib
Indications: Multiple myeloma (MM)
Target: Chymotrypsin-like proteolytic (β5) site of the 20S proteasome
PDIDM027
Moexipril
Active compound: Moexiprilat
Indications: Hypertension and congestive heart failure
Target: Angiotensin-converting-enzyme
PDIDM028
Molsidomine
Active compound: Linsidomine
Indications: Ischemic heart disease, angina, chronic heart failure, and pulmonary hypertension
Target: Hyperpolarizes cell membrane
PDIDM029
Moxisylyte
Active compound: Deacetylthymoxamine
Indications: Erectile dysfunction
Target: α1-adrenergic antagonist
PDIDM030
Mycophenolate Mofetil
Active compound: Mycophenolic Acid (MPA)
Indications: Used as immunosuppressant in solid-organ transplantation; Autoimmune hepatitis
Target: Inosine monophosphate dehydrogenase (impdh)