Showing results for 'F'
Total number of hits: 28
Click on results for more details:
PDIDF001
Famciclovir
Active compound: Penciclovir
Indications: Herpesvirus infections; varicella zoster virus (VZV)
Target: DNA polymerase catalytic subunit
PDIDF002
Faropenem Medoxomil
Active compound: Faropenem
Indications: Bacterial infection (staphilococcus)
Target: Peptidoglycan synthase FtsI
PDIDF003
Favipiravir
Active compound: Favipiravir riboside triphosphate
Indications: Influenza
Target: viral RNA polymerase
PDIDF004
F-dAdo
Active compound: 2-Fluoroadenine
Indications: Tumors
Target: Purine nucleoside phosphorylase DeoD-type
PDIDF005
Fenofibrate
Active compound: Fenofibric acid
Indications: Primary hypercholesterolemia or mixed dyslipidemia; Hypertriglyceridemia (KEGG)
Target: Peroxisome proliferator-activated receptor alpha
PDIDF006
Fesoterodine
Active compound: 5-hydroxymethyltolterodine
Indications: Urinary incontinence
Target: M2 and M3 muscarinic receptors
PDIDF007
Fingolimod
Active compound: Fingolimod-phosphate
Indications: Multiple sclerosis
Target: Sphingosine 1-phosphate (S1P) receptor
PDIDF008
Flucytosine
Active compound: 5-Fluorouridine 5'-triphosphate
Indications: Candida or Cryptococcus neoformans fungal infections
Target: DNA
PDIDF009
Fludarabine
Active compound: Fludarabine triphosphate
Indications: B-cell chronic lymphocytic leukemia
Target: Ribonucleoside-diphosphate reductase subunit M1; DNA polymerase; cytosolic 5′-nucleotidase II
PDIDF010
Fluphenazine decanoate
Active compound: Fluphenazine
Indications: Psychoses; Schizophrenia
Target: Dopamine receptor D2
PDIDF011
Fluphenazine enanthate
Active compound: Fluphenazine
Indications: Psychoses; Schizophrenia
Target: Dopamine receptor D2
PDIDF012
Flurbiprofen axetil
Active compound: Flurbiprofen
Indications: pain in cancer disease
Target: Prostaglandin-endoperoxide synthase 1 and prostaglandin-endoperoxide synthase 2 (KEGG)
PDIDF013
Flutamide
Active compound: Hydroxyflutamide
Indications: Prostate cancer
Target: Androgen receptor
PDIDF014
Fmoc-Lys(Ac)-Puromycin
Active compound: Puromycin
Indications: Cancer
Target: 60S ribosomal protein
PDIDF015
Fosamprenavir
Active compound: Amprenavir
Indications: HIV infections
Target: HIV Protease
PDIDF016
Fosaprepitant
Active compound: Aprepitant
Indications: Antiemetic; Vomiting and nausea
Target: Neurokinin 1 (NK1) receptor
PDIDF017
Fosbretabulin
Active compound: Combretastatin A4
Indications: Thyroid cancer
Target: Tubulin
PDIDF018
Fosciclopirox (CPX-POM)
Active compound: Ciclopirox
Indications: Advanced solid tumors
Target: na
PDIDF019
Fosfluconazole
Active compound: Fluconazole
Indications: 1) Vaginal yeast infections caused by Candida 2) Systemic Candida infections 3) Both esophageal and oropharyngeal candidiasis 4) Cryptococcal meningitis 5) UTI (urinary tract infection) by Candida 6) Peritonitis (inflammation of the peritoneum) caused by Candida
Target: Sterol 14alpha-demethylase (KEGG)
PDIDF020
Fosinopril
Active compound: Fosinoprilat
Indications: Hypertension and congestive heart failure
Target: Angiotensin-converting-enzyme
PDIDF021
Fosnetupitant
Active compound: Netupitant
Indications: Acute and delayed nausea and vomiting associated with moderately emetogenic cancer chemotherapy; acute and delayed nausea and vomiting associated with highly emetogenic cisplatin-based cancer chemotherapy
Target: Neurokinin-1 (NK-1) receptors
PDIDF022
Fosphenytoin
Active compound: Phenytoin
Indications: Epilepsy
Target: Sodium channel protein type 5 subunit alpha
PDIDF023
Fospropofol
Active compound: Propofol
Indications: General anesthesia
Target: GABAA receptor
PDIDF024
Fostamatinib
Active compound: R406
Indications: Rheumatoid Arthritis and Immune Thrombocytopenic Purpura (ITP)
Target: Spleen tyrosine kinase; adenosine a3 receptor; adenosine and monoamine uptake transporters; udp glucuronosyltransferase ugt1a1; phosphodiesterase pde5; fatty acid amide hydrolase; 5-lipoxygenase, cathepsin l; and cathepsin s
PDIDF025
Fostemsavir
Active compound: Temsavir
Indications: HIV-1
Target: gp120 molecule on Virus surface (Ref 1)
PDIDF026
Frueh_etal_2017_ELQ-331
Active compound: ELQ-300
Indications: Malaria
Target: Plasmodium falciparum cytochrome bc1 complex
PDIDF027
FTI 277
Active compound: FTI 276
Indications: Multiple myeloma
Target: Farnesyl transferase
PDIDF028
Fursultiamine
Active compound: Thiamine
Indications: Vitamine B1 deficiency
Target: na