Showing results for 'I'
Total number of hits: 12
Click on results for more details:
PDIDI002
Ibuprofen piconol
Active compound: Ibuprofen
Indications: Pain and inflammation; atopic dermatitis
Target: Prostaglandin-endoperoxide synthase 1 and prostaglandin-endoperoxide synthase 2 (KEGG)
PDIDI004
Imidapril
Active compound: Imidaprilat
Indications: Hypertension
Target: Angiotensin-converting-enzyme
PDIDI006
Indomethacin farnesil
Active compound: Indomethacin
Indications: Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Bursitis, Osteoarthritis (OA), Pain (Acute), Patent Ductus Arteriosus (PDA), Rheumatoid Arthritis, Tendinitis (DrugBank)
Target: Prostaglandin-endoperoxide synthase 1 and prostaglandin-endoperoxide synthase 2 (KEGG)
PDIDI008
Isavuconazonium
Active compound: Isavuconazole
Indications: Invasive aspergillosis and Invasive mucormycosis
Target: lanosterol 14-alpha-demethylase (Ref 1); cytochrome P450 3A4 (CYP3A4/5) (Ref 2)
PDIDI009
Isoniazid
Active compound: Isonicotinic Acyl redical
Indications: Tuberculosis (TB)
Target: Enoyl-acyl carrier protein reductase (inha); Catalase-peroxidase
PDIDI014
Ixazomib citrate
Active compound: Ixazomib
Indications: Multiple Myeloma (MM)
Target: 20S proteasome
PDIDM026
MLN9708
Active compound: Ixazomib
Indications: Multiple myeloma (MM)
Target: Chymotrypsin-like proteolytic (β5) site of the 20S proteasome
PDIDA024
Acemetacin
Active compound: Indometacin
Indications: Osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain
Target: Cyclooxygenase (COX)
PDIDA028
Aconiazide
Active compound: Isoniazide
Indications: Tuberculosis
Target: Cell specific
PDIDP040
ProINDY
Active compound: INDY
Indications: Down syndrome
Target: Dual-specificity tyrosine-(y)-phosphorylation-regulated kinase 1a
PDIDR019
Ropidoxuridine
Active compound: Idoxuridine
Indications: Radiosensitizer
Target: Thymidylate synthase
PDIDA049
ANA971
Active compound: Isatoribine
Indications: Hepatitis C virus
Target: Toll-like receptor 7